Many infections do not cause any symptoms in otherwise healthy people. The immune system is suppress the virus ' activity, leading to a human being is the carrier of the infection. The transfer of pathogens to other people, even when full clinical well-being because of the viral particles, please refer to the water trickling from the patient. Invisible for an infection, you may be one of the main significant cause of the spread of the disease, the patient in a timely manner, do not go to research, and will continue to infect other people are irresponsible.
The human papilloma virus (HPV) can be an excellent example of the hidden, of an infectious agent. The majority of the people are infected with at least one type of HPV in the course of a lifetime, however, the clinical manifestations of the disease occur, they do not in all cases. The end complications of the infection, the doctors are related to an increased risk of the formation of a malignant tumor. Patients who suffer from primary immune deficiency diseases, many of the times it is a negative consequence of the disease. Topical medications help suppress the symptoms of the HPV infection. It is also recommended that vaccination in good time.
You can read more about the disease
The human papilloma virus is the causative agent of this infection, which attacks the skin and the mucous membranes of the body. The main manifestation of the disease is in the rise of cancer in the facial region, the genitalia, the mouth and the throat. In some cases, a fine of infection are formed, which are not specific places, such as the skin, the lower and upper extremities. The location of the cells depends on the type of HPV. The majority of people, infection leads to the strengthening of the transport of infection, however, is by reducing the it can increase the immunity to the virus starts to express its virulence. In some cases, the immunocompetent cells to self-destroy the pathogen during the first 3 to 6 months after the invasion of the body.
Infection with HPV is the most common type of the disease, and sexually transmitted diseases. This may explain the high virulence virus, and is asymptomatic current of disease in the vast majority of people. The use of a condom does not always prevent infection, so the patient can continue to spread the virus, even when it's protected by the sexual contacts. At the same time, experts have developed effective vaccines to prevent the development of the oncogenic form of HPV. Seth shows off the girls in the teenage years, such as the protection against viruses is to inculcate it before the first sexual contact.
The characteristics of the virus
The human papilloma virus is a DNA containing a microbe pathogenic. On the contrary, bacteria, and other micro-organisms, and viruses can exert their activity only after the implementation on the web, and the incorporation of genetic information into the nucleus. After that, you scared the pile begins to synthesize proteins that are required for the assembly of viral particles. Almost all of the representatives of the family, the human to attack only one kind of organisms, and infection with HPV can occur with just one person.
Scientists think they know more than 600 strains (types) of human papilloma virus, differing in the genetic information. The 40 types of HPV that cause different forms of injury to the mucous membranes and the skin. When you do this, the major clinical significance is a rating of the degree of oncogenetic strains. Thus, cervical cancer in women, occurs most frequently in the invasion of HPV 16 and 18 types. These infectious agents do not always manifest in the skin, change.
HPV infects the basal layer of the epithelium. The pathogen may be in the form of episome, are not related to the DNA in the cell, or in an integrated way, related to the genome of the cell. It is integrated into the virus to produce the protein, and is called the clinical manifestations of the disease. The functions of the HPV in the body is not the immediate cause of the transformation to a malignant tissue, however, they may be a carrier of the virus, increases the risk of the risk factors for lung cancer.
Methods of infection
The virus is contained in the epithelial cells and, therefore, any of the microtrauma to the skin and mucous membranes, increase the risk of hiv infection. In the majority of cases, HPV is transmitted through sexual intercourse-vaginal, anal, or oral sexual contact. A condom can protect only a portion of the surface of the skin, however, the virus particles that could enter the body through the blinds. The presence of the cells in the body it makes the transmission of the pathogen, but it is, apparently, intact skin of a carrier of the disease, it is also a source of HPV.
Other forms of transmission
- The infection of the child during birth. This is most likely to occur in lesions of the upper respiratory tract
- Regardless of the transfer of the virus to a part of the body to another
- The use of objects of personal hygiene, including the blades, razor, toothbrush, and towel
- The loss of blood. Recent studies of have confirmed the ability of the blood to the infection.
- Surgery under non-sterile conditions
In spite of a variety of causes, from viruses, to hacking, only the sex of HPV has clinical significance in. Other sources of infection are characterized by a low risk of the spread of the pathogen.
The risk factors for
In addition to the immediate means of transmission of HPV, it is important to consider the role of other known risk factors. It is characteristic of the style of a person's life, and, in some states in the physical.
The main risk factors for the infection
- A large number of sexual partners you have. Even when you practice safer sex with an active sexual life, and sooner or later leads to infection.
- Age. The cells in the body in most of the cases are found in adolescents and young patients, whereas condylomata of the oral cavity and the respiratory tract are typical for the child.
- Saying goodbye to the immune system. Patients who are suffering from HIV infection or acquired immune deficiency syndrome, are not exposed to the virus and break-in. Also, HPV is more frequently are symptomatic after transplantation of the organ.
- Injury to the skin and mucous membranes. Microtrauma to facilitate the penetration of the virus into the basal layer of the epithelium.
- Smoking and alcohol abuse. The bad habits will diminish the activity of the immune system.
- The urinary tract infection.
In addition to this, the at-risk group is pregnant women. It should be kept in mind that the elimination of the predisposing factors to the disease, is effective as a preventive tactic.
jpg" class="imgblock right "center_mob">The clinical course of the
The period of incubation, before the onset of the disease can last for months, or you don't. You patients are immunocompetent, during this time, the body can destroy the an infection, however, spontaneous elimination of the pathogen is not always the case. Can a person be infected with multiple strains of the virus. Signs of an HPV infection occurs when the impact of the factors are hard, weakening of the immune system, protecting the body's tissues. Due to the applicant's chain of condyloma periodically disappear and are created again and again. Patients who suffer from complications of the infection can develop in several years to come.
The implications of the ailment.
- Cancer of the cervix of the uterus, a tumor of a malignant new growth of epithelial tissue. This is a type of cancer associated with the human papilloma virus. When appropriate to the immunization, to the risk of oncogenesis decreases.
- The squamous children the anal. This complication can occur in both men and women. The early symptoms of cancer of the anus, include haemophilia, and itching of the skin.
- A violation of urination due to obstruction of the urethra, the the the cells.
- Malignant Tumor of the rebirth of the cells in the region of the throat and mouth.
Cancer of the cervix of the uterus, is one of the most frequent causes of death in women. Because of this disease, it is related to the virus invasion, you need to set the pass-through surveys along with to a gynecologist. Modern vaccines can protect women from most of the oncogenic types of HPV.
The diagnosis
The observation of the genitalia are gynecologists, urologists, venereologists and dermatologists. During the first admission, the doctor will ask you questions about all the complaints of the patient, you're going to gather anamnestic data and to carry out the inspection of the skin patterns. Normally, the manifestation of HPV is detected, however, it is necessary to rule out other diseases. To this end, the specialist will prescribe the tools, and laboratory studies.
Methods of diagnosis:
- Set of tools for the inspection of the vagina and the cervix (colposcopy). The study was necessarily performed for the screening of cervical cancer of the uterus (womb). During the physical examination, the doctor is able to detect multiple infection, and the areas of dysplasia, the epithelial.
- Once the receipt of the material and the tissue in the area of diseases of the skin or mucous membrane changes. Cytologic screening of the sample allows us to identify malignant cells.
- Polymerase chain reaction detection of viral particles of HPV in the body. To carry out this test gives the physician the possibility to determine the type of pathogen, and the viral load.
- Digene-test, the high accuracy of the detection of the DNA oncogenic strains of the human papilloma virus. The research takes as a reliable screening.
Medical treatment
Developed drugs against an HPV infection, they can only eliminate the symptoms of the disease and to prevent cancer tissues. The Total elimination of the virus with the help of a medical therapy is no longer possible. Oral and topics on the tools they are assigned to, in the case of a high risk of oncogenesis, immune deficiency, and of any other steroids in terms. If the virus does not manifest itself by changes in the external and the common good of the preventive measures.
A possible target
- Salicylic acid to remove warts. It is not used for the treatment of the skin on the face and genitals.
- Topical creams and ointments that contain immunomodulatory and tools.
- Podofilox – ointment with cytotoxic action. The application of medicines to the affected skin leads to the destruction of pathogens.
- Trichloroacetic acid to the caustic chemical-general and the cells in the body. It can cause you to the local cap's expression.
Listed on on medication must only be used under the sheet summary of the health of the control. After the removal of the warts, the HPV infection may manifest itself again, and even if it has spread to other areas as well.
Surgical treatment
Your doctor may suggest the surgical patient and minimally invasive ways to eliminate warts. Typically, these methods do not cause any complications, however, in the first few days after surgery bleeding may occur from the tissue.
Types of services:
- the normal is the surgical removal;
- freeze in nitrogen, liquid oxygen, to the rear is a bum damaged tissues;
- the electrical coagulation;
- removal of papillomas with a laser beam.;
- the use of radiowave "the knife".
All of the procedures for passing under a local anaesthetic. An expert in selecting the best and most secure method of the treatment of the body.
Forecast
For papilomasaviruses infection depends on the status and immune response of the patient, and the particular strain of the virus. About 30% of the population occurs in the spontaneous elimination of the causative agent of the disease, is due to be up and running you can enhance immunity. They are symptoms of the disease are often seen in women who are pregnant, children, the elderly, and patients with weak immune systems.
The HPV infection is a characteristic repeat time. Established, papilloma virus, may be gradually disappearing, or spreading to areas of the skin. Oncogenic strains of the virus, most often affecting the mucous membrane of the cervix of the uterus, which occurs in the epithelial dysplasia, it increases the effect of the factors on the risk of transformation to malignant tissue, such as cigarette smoking and use of oral contraceptives. The tumor may also be formed from 10 to 20 years after the invasion of the virus into the body.
Prevention
The safest method of prevention is prior to immunization. The vaccine, Gardasil, which contains both viral proteins and components of the auxiliary, to be effective against HPV 6, 11, 16 and 18 types. If the vaccination is carried out at the beginning of the age of the first sexual contact, the risk of subsequent development of cancer of the cervix of the uterus in the female, which does not exceed 1 per cent.
More on prevention:
- the use of a rights-based approach;
- sex only with proven partners.
- careful personal hygiene;
- gynecological examination at least once a year.